Structural deficit in remitted and non-remitted recurrent depression: A voxel-based morphometric study
نویسندگان
چکیده
P-C. Chen, K-H. Chou, I-Y. Chen, H-H. Wang, C-T. Li, T-P. Su, and C-P. Lin Institute of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, Institute of Biomedical Engineering, National Yang-Ming University, Taipei, Taiwan, Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan, Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan
منابع مشابه
Structural and cognitive deficits in remitting and non-remitting recurrent depression: A voxel-based morphometric study
Remission is the optimal outcome for major depressive disorder (MDD), but many patients do not improve appreciably despite treatment with medication. Treatment-resistant patients may experience deterioration in cognitive functions. Research has reported structural abnormalities in certain brain areas that may contribute to a poor clinical response. We hypothesize that there will be structural d...
متن کاملInferior Frontal and Cingulate Volume as Markers of Poor Outcome in Depression Brain morphometry changes in MDD over 2 years
Early prediction of recurrence of depressive episodes in major depressive disorder (MDD) is key for prevention and decreasing disease burden. We investigated 1) the predictive value of regional brain volume abnormalities (anterior and posterior cingulate, inferior frontal gyrus, and hippocampus) for recurrence or recovery over a 2-year interval; and 2) whether structural changes progressed with...
متن کاملStructural Brain Changes as Biomarkers and Outcome Predictors in Patients with Late-Life Depression: A Cross-Sectional and Prospective Study
The relationship between structural changes in grey matter and treatment response in patients with late-life depression remains an intriguing area of research. This magnetic resonance imaging (MRI) study compares the baseline grey matter volume of elderly people with and without major depression (according to the DSM-IV-TR criteria) and assesses its association with antidepressant treatment res...
متن کاملLarger regional white matter volume is associated with executive function deficit in remitted geriatric depression: an optimized voxel-based morphometry study.
OBJECTIVE We aimed to investigate structural abnormalities in first-episode remitted geriatric depression (RGD) using optimized voxel-based morphometry (VBM) in closely matched patients and healthy controls, and examining the relationship of performances on neuropsychological tests with regional white matter volumes. METHODS Forty subjects with first-episode RGD and 36 well-matched healthy co...
متن کاملChanges in gray matter volume of remitted first-episode, drug-naïve, panic disorder patients after 6-week antidepressant therapy.
OBJECTIVE This study aimed to investigate changes in the gray matter volume (GMV) of first-episode, remitted drug-naïve patients under 6 weeks of escitalopram treatment for panic disorder (PD). We also determined any persistent GMV deficits after remission to assess for "state-dependent brain changes" and "trait-like brain changes" for PD. METHOD 3-Tesla magnetic resonance imaging structural ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2008